In 1906, the Pure Food and Drug Act became the landmark Progressive Era legislation signed into law. It regulated food and drugs moved between states and forbade the manufacture, sale or transportation of poisonous patent medicines. Support for the law, including from the President, arose from exposés by such muckrakers as Upton Sinclair and Samuel Hopkins Adams.

President Theodore Roosevelt also signed the Federal Meat Inspection Act. The U.S. Department of Agriculture enforced both the Pure Food and Drug Act and the Meat Inspection Act.

Source: Pure Food and Drug Act Passes, June 23, 1906
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